InACTIVatINg cancer cachexia
نویسندگان
چکیده
منابع مشابه
InACTIVatINg cancer cachexia
a debilitating muscle-and fat-wasting condition that is associated with multiple diseases, including cancer, diabetes, AIDS and tuberculosis, as well as injuries. Estimates reveal that up to 80% of all cancer patients suffer from cachexia, which not only leads to a decrease in the quality of life due to impaired mobility but also accounts directly for ~20% of cancer-related deaths (Fearon, 2008...
متن کاملCancer Cachexia
Cancer anorexia-cachexia (CACS) is defined as a multifactorial syndrome characterized by ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment [1]. Cancer cachexia occurs across a continuum, varying in severity and stage; according to new classification we have pre-cachexia (early clinical signs of c...
متن کاملCancer anorexia - cachexia syndrome.
Cancer anorexia-cachexia syndrome (CACS) is a devastating and debilitating aspect at any stage of malignancy. It presents primarily as anorexia, weight loss and muscle wasting secondary to inadequate oral intake and metabolic changes. This syndrome is highly prevalent among cancer patients, has a large impact on morbidity and mortality, and impinges on patient quality of life. The pathogenic me...
متن کاملCancer cachexia and fatigue.
Cachexia is a disease process that develops in numerous chronic, end-stage disease processes (eg cancer, heart failure, AIDS, renal failure). It has no agreed definition but represents the complex metabolic process that occurs in patients with these conditions.1 Cachectic patients lose lean muscle mass as well as fat, unlike starvation where only fat stores are initially depleted. In addition, ...
متن کاملNew cancer cachexia model
1 New cancer cachexia rat model generated by implantation of a peritoneal 1 dissemination-derived human stomach cancer cell line 2 3 Kiyoshi Terawaki, Yumi Sawada, Yohei Kashiwase, Hirofumi Hashimoto, Mitsuhiro 4 Yoshimura, Masami Suzuki, Kanako Miyano, Yuka Sudo, Seiji Shiraishi, Yoshikazu Higami, 5 Kazuyoshi Yanagihara, Yoichi Ueta, and Yasuhito Uezono 6 Division of Cancer Pathophysiology, Na...
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ژورنال
عنوان ژورنال: Disease Models & Mechanisms
سال: 2011
ISSN: 1754-8411,1754-8403
DOI: 10.1242/dmm.007658